Abstract: A mixed reality cockpit interface design method based on the pilots personalized feature adaptation is proposed, the background information of pilots, such a special user group is taken fully into consideration. On the basis of the original interface design process, the user personalized influencial factors are mapped to the relevant contents of information architecture, layout, interaction flow, visual and other design processes, and the corresponding design strategies are generated. First, according to the imaging characteristics of MR, the layout division of the original physical interface and virtual interface is completed, and the relevant design demonstration is completed in combination with the specific scenarios. Finally, the personalized adaption of the interface is realized by user identification and preference settings.