Abstract: In recent years, the development of large scale pre-trained model （LSPTM）has produced unexpected effects in the field of artificial intelligence, especially the breakthrough of ChatGPT in natural language processing（NLP） , which seems to open up the key to a door of "artificial intelligence", and in just a few months, its intelligence has achieved a leap from human understandable intelligence to incomprehensible intelligence. The LSPTM represented by ChatGPT is about to open a new era of silicon-based intelligence, and command and control （C2） , as a key element of embodying intelligence that human society is proud of, what opportunities and challenges will it face? Guided by the basic paradigm and operation mode framework of the C2 process, this paper comprehensively analyzes the potential application of LSPTM in the physical, information, cognitive and social domains of command and control activities, and explains the leap of artificial intelligence from auxiliary tool role to partner and alternative role in the era of silicon-based intelligence, and the development opportunities of command and control field. The competition of confrontational C2 in the military field is no longer limited to technology, but cultivates the cultural heritage of LSPTM, and the difference between Eastern and Western cultures and values will determine the wisdom and intelligence of two different LSPTM.