Abstract: UAV swarm system is a new quality and important combat force for system confrontation in modern information warfare, which is the key development direction for future networked and intelligent combat. With the breakthrough of actualization technology of unmanned swarm system equipment, it brings great challenges to the existing system countermeasures. Large scale of unmanned swarm system countermeasures and confrontation problems are the research difficulties of future system confrontation. The key issues of group dynamics evolution control, enemy swarm statistical feature identification inference and swarm confrontation situation effectiveness assessment are analyzed by combining the typical mission scenarios and combat processes of swarm confrontation. Then the corresponding key technologies for UAV swarm confrontation are discussed, including opponent modeling based on limited observational information, incomplete information dynamic game for UAV swarm confrontation, and swarm pinning control combined with virtual leaders. Finally, the difficulties and challenges in theoretical research and practical application are analyzed based on the operationalcharacteristics and mission requirements of UAV swarm confrontation.